Description

5-Bromo-n-(Tetrahydro-2H-Pyran-4-Yl)Pyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS registry number 1307606-48-9. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting complex disease pathways. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing more complex heterocyclic compounds and functionalized sulfonamides.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe for investigating biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and scale-up services for clinical trial materials.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis and drug discovery projects.

Basic Information

Product Name	5-Bromo-n-(Tetrahydro-2H-Pyran-4-Yl)Pyridine-3-Sulfonamide
CAS No.	1307606-48-9
Molecular Formula	C10H13BrN2O3S
Molecular Weight	321.19 g/mol
Synonyms	5-Bromo-N-(tetrahydro-2H-pyran-4-yl)pyridine-3-sulfonamide; 3-Pyridinesulfonamide, 5-bromo-N-(tetrahydro-2H-pyran-4-yl)-; 1307606-48-9; 5-Bromo-N-(oxan-4-yl)pyridine-3-sulfonamide; 5-Bromo-3-pyridinesulfonamide, N-(tetrahydro-2H-pyran-4-yl)-; 5-Bromo-N-tetrahydropyran-4-ylpyridine-3-sulfonamide; 5-Bromo-N-(tetrahydropyran-4-yl)pyridine-3-sulfonamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(Tetrahydro-2H-Pyran-4-Yl)Pyridine-3-Sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.