Description

7-Bromo-6-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides versatile reactivity for constructing complex molecular architectures. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and anticancer research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromine and chlorine atoms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, functionalized isoquinoline cores.

Basic Information

Product Name	7-Bromo-6-Chloroisoquinoline
CAS No.	1307316-83-1
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	6-Chloro-7-bromoisoquinoline; Isoquinoline, 7-bromo-6-chloro-; 7-Bromo-6-chloro-isoquinoline; 1307316-83-1; 6-Chloro-7-bromo-isoquinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Chloroisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.