Description

2-Bromo-(n-Boc-4-Piperazinyl)Prop-1-Ene is a specialized, high-purity chemical building block featuring a reactive bromoalkene group and a protected piperazine moiety. This compound matters as a critical intermediate in modern pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel drug candidates, particularly in areas like kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce functionalized piperazine scaffolds.
• Process Research & Development: Serves as a versatile intermediate for scaling up synthetic routes under GMP-like conditions.
• Bioconjugation & Probe Development: The reactive bromoalkene group can be utilized for click chemistry and labeling applications in chemical biology.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Academic Research: Used in university and institutional labs for developing new synthetic methodologies and exploring novel chemical space.

Basic Information

Product Name	2-Bromo-(n-Boc-4-Piperazinyl)Prop-1-Ene
CAS No.	1306746-97-3
Molecular Formula	C12H21BrN2O2
Molecular Weight	305.21 g/mol
Synonyms	1-Boc-4-(2-Bromoallyl)piperazine; tert-Butyl 4-(2-bromoallyl)piperazine-1-carboxylate; 2-Bromo-1-(1-Boc-piperazin-4-yl)prop-1-ene; 4-(2-Bromoallyl)-1-Boc-piperazine; N-Boc-4-(2-bromoallyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-bromoallyl)piperazine; 2-Bromoallyl piperazine Boc derivative
EINECS	Contact for details

Quality Control

Our 2-Bromo-(n-Boc-4-Piperazinyl)Prop-1-Ene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.