Description

2-[1-(Chloroacetyl)-3-Oxopiperazin-2-Yl]-n-[3-(Trifluoromethyl)Phenyl]Acetamide CAS NO 1306738-22-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Used in the research and synthesis of potential chemotherapeutic agents and targeted cancer therapies.
• CNS-Active Compound Synthesis: Employed in the development of new molecules targeting neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and scale-up.
• Process Chemistry & Route Scouting: Utilized for developing and optimizing efficient, scalable synthetic routes for complex molecules.

Basic Information

Item	Details
Product Name	2-[1-(Chloroacetyl)-3-Oxopiperazin-2-Yl]-n-[3-(Trifluoromethyl)Phenyl]Acetamide
CAS No.	1306738-22-6
Molecular Formula	C15H15ClF3N3O3
Molecular Weight	389.75 g/mol
Synonyms	N-[3-(Trifluoromethyl)phenyl]-2-[1-(chloroacetyl)-3-oxopiperazin-2-yl]acetamide; 2-[1-(Chloroacetyl)-3-oxo-2-piperazinyl]-N-[3-(trifluoromethyl)phenyl]acetamide; 1306738-22-6; Acetamide, 2-[1-(chloroacetyl)-3-oxo-2-piperazinyl]-N-[3-(trifluoromethyl)phenyl]-; 2-(1-(Chloroacetyl)-3-oxopiperazin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-[1-(Chloroacetyl)-3-Oxopiperazin-2-Yl]-n-[3-(Trifluoromethyl)Phenyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.