Description

2-(Piperazin-1-Yl)Propanamide Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its dihydrochloride salt form, which enhances stability and handling properties. This compound is of significant value in medicinal chemistry for the synthesis of novel therapeutic agents, particularly those targeting central nervous system and metabolic disorders. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to improve drug efficacy and safety profiles.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies to investigate specific biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	2-(Piperazin-1-Yl)Propanamide Dihydrochloride
CAS No.	1306602-96-9
Molecular Formula	C7H16N4O · 2HCl
Molecular Weight	269.15 g/mol
Synonyms	2-(Piperazin-1-yl)propanamide dihydrochloride; 1-(1-Amino-1-oxopropan-2-yl)piperazine dihydrochloride; Propanamide, 2-(1-piperazinyl)-, dihydrochloride; UNII-9K2V7138WY; 9K2V7138WY; 2-Piperazin-1-ylpropionamide dihydrochloride; 2-(Piperazin-1-yl)propionamide dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-Yl)Propanamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.