Description

5-Chloro-6-(Dimethoxymethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in pharmaceutical discovery, serving as a key intermediate in the synthesis of complex bioactive molecules. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel pyrrolopyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce complex fused-ring systems into target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.

Basic Information

Product Name	5-Chloro-6-(Dimethoxymethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1305324-72-4
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	5-Chloro-6-(dimethoxymethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-6-(dimethoxymethyl)-; 6-(Dimethoxymethyl)-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-(dimethoxymethyl)-7-azaindole; 5-Chloro-6-(dimethoxymethyl)-1H-7-azaindole; 5-Chloro-6-(dimethoxymethyl)pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Dimethoxymethyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines for impurities and can provide material suitable for use under GMP conditions for non-clinical studies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.