Description

2-Chloro-6-Iodo-3-Pivalamidoisonicotinic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated and amide-substituted pyridine structure makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Chemical Biology Probe Synthesis: Employed to create labeled or modified compounds for studying biological pathways and protein interactions.
• Material Science Research: Acts as a building block for synthesizing specialized ligands, catalysts, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-6-Iodo-3-Pivalamidoisonicotinic Acid
CAS No.	1305324-54-2
Molecular Formula	C11H10ClIN2O3
Molecular Weight	380.56 g/mol
Synonyms	3-Pivalamido-2-chloro-6-iodoisonicotinic Acid; 2-Chloro-6-iodo-3-[(2,2-dimethylpropanoyl)amino]isonicotinic Acid; 2-Chloro-6-iodo-3-(pivalamido)isonicotinic Acid; 1305324-54-2; Isonicotinic acid, 2-chloro-6-iodo-3-[(2,2-dimethyl-1-oxopropoxy)amino]-; 2-Chloro-6-iodo-3-(2,2-dimethylpropanamido)isonicotinic Acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Iodo-3-Pivalamidoisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.