Description

3,6-Dibromo-[1,2,4]triazolo[4,3-a]pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a brominated pyridine scaffold with a fused triazole ring, making it an essential precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the dibromo-triazolopyridine core can impart unique modes of action.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of the molecular structure.
• Ligand Synthesis: Utilized for constructing complex nitrogen-containing ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	3,6-Dibromo-[1,2,4]triazolo[4,3-a]pyridine
CAS No.	1305208-13-2
Molecular Formula	C6H2Br2N4
Molecular Weight	289.91 g/mol
Synonyms	3,6-Dibromo-[1,2,4]triazolo[4,3-a]pyridine; 3,6-Dibromo-1,2,4-triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine, 3,6-dibromo-; 1305208-13-2; 3,6-Dibromo-s-triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 3,6-Dibromo-[1,2,4]triazolo[4,3-a]pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.