Description

5-Methyl-3-[[(2R)-4-(2-Thiazolylmethyl)-2-Morpholinyl]Methyl]-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-7-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its potential role as a key building block in novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Kinase Inhibitor Development: Its triazolopyrimidine core structure suggests potential application in the research of kinase inhibitors, a major class of targeted cancer therapies.
• Biochemical Assay Standards: Can be employed as a reference standard or analytical control in bioassay development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Item	Detail
Product Name	5-Methyl-3-[[(2R)-4-(2-Thiazolylmethyl)-2-Morpholinyl]Methyl]-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-7-Amine Hydrochloride
CAS No.	1305116-67-9
Molecular Formula	C16H22ClN9OS
Molecular Weight	423.93 g/mol
Synonyms	5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride; (R)-5-Methyl-3-((4-(thiazol-2-ylmethyl)morpholin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine hydrochloride; UNII-9J8K4A8U3B; 9J8K4A8U3B; CHEMBL3186660; BDBM50157871; AKOS025147065
EINECS	Contact for details

Quality Control

Our 5-Methyl-3-[[(2R)-4-(2-Thiazolylmethyl)-2-Morpholinyl]Methyl]-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-7-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and comprehensive identification tests. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.