Description

(R)-Valiolamine Voglibose CAS NO 1303996-67-9 is a high-purity, synthetic amino sugar derivative and a key intermediate in the production of the α-glucosidase inhibitor voglibose. This compound is critical for pharmaceutical research and development, particularly in the synthesis of novel anti-diabetic therapeutics. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in metabolic disorder drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of Voglibose, an oral anti-diabetic drug used to treat type 2 diabetes.
• Biochemical Research: Used in enzymatic studies as a potent and selective inhibitor of α-glucosidase for investigating carbohydrate metabolism pathways.
• Process Development: Serves as a reference standard and starting material for optimizing and scaling up the manufacturing process of Voglibose and its analogs.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final chemical steps for the production of high-purity Voglibose API under GMP conditions.
• Academic Research: Utilized in medicinal chemistry programs to develop new glycosidase inhibitors with potential therapeutic applications.

Basic Information

Product Name	(R)-Valiolamine Voglibose
CAS No.	1303996-67-9
Molecular Formula	C7H15NO5
Molecular Weight	193.20 g/mol
Synonyms	(3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)piperidine; (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol; Valiolamine; (R)-Valiolamine; Voglibose Intermediate; BA-1; BA1; AD-1
EINECS	Contact for details

Quality Control

Our (R)-Valiolamine Voglibose is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, chiral purity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.