Description

(S)-Valiolamine Voglibose CAS NO 1303996-66-8 is a high-purity, synthetic pharmaceutical intermediate and active pharmaceutical ingredient (API) derived from valiolamine. This compound matters as a key chiral building block in the synthesis of advanced α-glucosidase inhibitors, which are critical for managing postprandial hyperglycemia. It is primarily needed by pharmaceutical R&D laboratories, API manufacturers, and fine chemical suppliers serving the global diabetes therapeutics market, where precise stereochemistry and consistent quality are paramount for drug efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of Voglibose and related anti-diabetic drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and production of α-glucosidase inhibitor APIs.
• Biochemical Research: Serves as a reference standard and tool compound for studying carbohydrate metabolism and enzyme inhibition mechanisms.
• Fine Chemical Synthesis: Employed in asymmetric synthesis for creating complex, biologically active molecules with specific stereocenters.
• Academic & Contract Research: Utilized in university and CRO settings for metabolic disorder research and novel drug discovery programs.

Basic Information

Product Name	(S)-Valiolamine Voglibose
CAS No.	1303996-66-8
Molecular Formula	C7H15NO5
Molecular Weight	193.20 g/mol
Synonyms	(3S,4S,5S,6S)-6-(Hydroxymethyl)piperidine-3,4,5-triol; (S)-Valiolamine; Valiolamine, (S)-; Voglibose Intermediate; 1-Deoxynojirimycin derivative; α-glucosidase inhibitor intermediate; (3S,4S,5S,6S)-6-(Hydroxymethyl)-3,4,5-piperidinetriol
EINECS	Contact for details

Quality Control

Our (S)-Valiolamine Voglibose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, chiral purity, and impurity profiles as determined by HPLC, NMR, and other relevant pharmacopeial methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.