Description

8-Piperazin-1-Yl-Naphthalen-2-Ol Dihydrochloride is a high-purity organic salt compound, recognized for its role as a key pharmaceutical intermediate and research chemical. Its value lies in providing a reliable and consistent building block for the synthesis of more complex molecules, particularly in medicinal chemistry. This product is essential for R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutic agents, especially within the fields of oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop and optimize lead compounds with potential therapeutic effects.
• Biochemical Reagent: Serves as a standard or reference material in analytical and bioassay development for pharmacological testing.
• Organic Synthesis: Utilized as a versatile precursor for constructing complex heterocyclic and polycyclic aromatic systems in academic and industrial research.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	8-Piperazin-1-Yl-Naphthalen-2-Ol Dihydrochloride
CAS No.	1303968-32-2
Molecular Formula	C₁₄H₁₉Cl₂N₃O
Molecular Weight	316.22 g/mol
Synonyms	8-(Piperazin-1-yl)naphthalen-2-ol dihydrochloride; 2-Naphthol, 8-(1-piperazinyl)-, dihydrochloride; 8-Hydroxy-2-(piperazin-1-yl)naphthalene dihydrochloride; 1-(8-Hydroxynaphthalen-2-yl)piperazine dihydrochloride; 8-Piperazin-1-ylnaphthalen-2-ol dihydrochloride; 1303968-32-2; 8-Piperazinyl-2-naphthol dihydrochloride
EINECS	Contact for details

Quality Control

Our 8-Piperazin-1-Yl-Naphthalen-2-Ol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.