Description

(6-Trifluoromethyl-Pyridin-2-Yl)-Methanol Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core and trifluoromethyl functional group. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine-containing motifs for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Fluorinated Compound Library: An important reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological pathways and target engagement.

Basic Information

Product Name	(6-Trifluoromethyl-Pyridin-2-Yl)-Methanol Hydrochloride
CAS No.	1303968-19-5
Molecular Formula	C7H7ClF3NO
Molecular Weight	213.59 g/mol
Synonyms	2-(Hydroxymethyl)-6-(trifluoromethyl)pyridine hydrochloride; (6-(Trifluoromethyl)pyridin-2-yl)methanol hydrochloride; 2-Pyridinemethanol, 6-(trifluoromethyl)-, hydrochloride; 6-(Trifluoromethyl)-2-pyridinemethanol hydrochloride; (6-Trifluoromethyl-2-pyridyl)methanol HCl
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Pyridin-2-Yl)-Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.