Description

2-Bromo-5-(1-Hydroxy-1-Methylethyl)Pyrazine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a tertiary alcohol group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, where the pyrazine core offers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, leveraging the bromine atom for further functionalization.
• Material Science Research: Employed in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) where functionalized heterocycles are required.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	2-Bromo-5-(1-Hydroxy-1-Methylethyl)Pyrazine
CAS No.	1303967-23-8
Molecular Formula	C7H9BrN2O
Molecular Weight	217.06 g/mol
Synonyms	2-Bromo-5-(2-hydroxypropan-2-yl)pyrazine; 5-(1-Hydroxy-1-methylethyl)-2-bromopyrazine; 2-Bromo-5-(1-hydroxy-1-methylethyl)pyrazine; 2-Bromo-5-(2-hydroxy-2-propyl)pyrazine; tert-Butyl alcohol, 1-(6-bromo-3-pyrazinyl)-; 1-(6-Bromo-3-pyrazinyl)-1,1-dimethylethanol
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(1-Hydroxy-1-Methylethyl)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.