Description

2-(5-Fluoropyridin-2-Yl)-2-Methylpropanenitrile is a high-purity fluorinated pyridine derivative, serving as a critical nitrile-containing building block in advanced organic synthesis. Its molecular structure makes it a valuable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluoropyridine moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2-(5-Fluoropyridin-2-Yl)-2-Methylpropanenitrile
CAS No.	1302580-97-7
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	2-(5-Fluoro-2-pyridinyl)-2-methylpropanenitrile; 2-Methyl-2-(5-fluoropyridin-2-yl)propanenitrile; 5-Fluoro-2-(2-cyano-2-propyl)pyridine; 2-(5-Fluoropyridin-2-yl)-2-methylpropionitrile; α,α-Dimethyl-5-fluoro-2-pyridineacetonitrile; 5-Fluoro-2-pyridineacetonitrile, α,α-dimethyl-; Propanenitrile, 2-(5-fluoropyridin-2-yl)-2-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Fluoropyridin-2-Yl)-2-Methylpropanenitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical and advanced chemical synthesis. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.