Description

3,6-Dibromopyrazine-2-Carboxamide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its versatile reactivity, where the bromine atoms serve as excellent handles for cross-coupling reactions and the carboxamide group provides a point for further functionalization. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of pyrazine-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with pyrazine cores.
• Material Science Research: Serves as a precursor for the synthesis of functional organic materials, such as ligands for catalysts or components for electronic materials.
• Cross-Coupling Reactions: The dibromo-substitution pattern makes it an ideal substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create diverse bi-aryl and hetero-aryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	3,6-Dibromopyrazine-2-Carboxamide
CAS No.	1301613-77-3
Molecular Formula	C5H3Br2N3O
Molecular Weight	280.90 g/mol
Synonyms	2,5-Dibromopyrazine-3-carboxamide; 3,6-Dibromo-2-pyrazinecarboxamide; 2-Pyrazinecarboxamide, 3,6-dibromo-; DBPC; Dibromopyrazinecarboxamide
EINECS	Contact for details

Quality Control

Our 3,6-Dibromopyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.