Description

[3-Chloro-5-Trifluoromethyl-1H-Pyridin-(2E)-Ylidene]-Cyano-Acetic Acid Ethyl Ester is a high-value, multi-functional chemical intermediate characterized by its unique pyridine core substituted with chloro, trifluoromethyl, and cyano-acetic ester groups. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its specific halogenated and fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of advanced organic electronic materials and dyes due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A vital component for fine chemical suppliers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	[3-Chloro-5-Trifluoromethyl-1H-Pyridin-(2E)-Ylidene]-Cyano-Acetic Acid Ethyl Ester
CAS No.	1300019-72-0
Molecular Formula	C11H6ClF3N2O2
Molecular Weight	290.63 g/mol
Synonyms	Ethyl (2E)-2-cyano-2-[3-chloro-5-(trifluoromethyl)-1H-pyridin-2-ylidene]acetate; (2E)-2-Cyano-2-[3-chloro-5-(trifluoromethyl)-1H-pyridin-2-ylidene]acetic acid ethyl ester; 3-Chloro-5-trifluoromethyl-1H-pyridin-2-ylidene-cyano-acetic acid ethyl ester; 2-(3-Chloro-5-(trifluoromethyl)-1H-pyridin-2(3H)-ylidene)-2-cyanoacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our [3-Chloro-5-Trifluoromethyl-1H-Pyridin-(2E)-Ylidene]-Cyano-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.