Description

6-Bromo-3-Chloro-8-Iodo-Imidazo[1,2-A]Pyridine is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates and functional materials, offering multiple reactive sites for selective functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique halogenated structure for bioactivity.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized to create tagged or labeled compounds for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of bromo and iodo substituents.
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	6-Bromo-3-Chloro-8-Iodo-Imidazo[1,2-A]Pyridine
CAS No.	1296223-94-3
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.38 g/mol
Synonyms	6-Bromo-3-chloro-8-iodoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-bromo-3-chloro-8-iodo-; 1296223-94-3; 6-Br-3-Cl-8-I-imidazo[1,2-a]pyridine; Multi-halogenated imidazopyridine; Halogenated imidazo[1,2-a]pyridine derivative
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-8-Iodo-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.