Description

3-(1,1-Difluoroallyl)Quinoxalin-2-Ol is a specialized heterocyclic organic compound featuring a quinoxaline core substituted with a difluoroallyl group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with potential enhanced efficacy.
• Ligand & Catalyst Development: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3-(1,1-Difluoroallyl)Quinoxalin-2-Ol
CAS No.	1294512-27-8
Molecular Formula	C₁₁H₈F₂N₂O
Molecular Weight	222.19 g/mol
Synonyms	2-Quinoxalinol, 3-(1,1-difluoro-2-propen-1-yl)-; 3-(1,1-Difluoroallyl)-2-hydroxyquinoxaline; 3-(1,1-Difluoro-2-propen-1-yl)quinoxalin-2-ol; 3-(Difluoroallyl)-2-hydroxyquinoxaline; 2-Hydroxy-3-(1,1-difluoroallyl)quinoxaline; Quinoxalin-2-ol, 3-(1,1-difluoroallyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(1,1-Difluoroallyl)Quinoxalin-2-Ol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filing support upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.