Description

cis-8-Benzyl 3-tert-Butyl 3,8-Diazabicyclo[4.2.0]Octane-3,8-Dicarboxylate CAS NO 1293940-93-8 is a high-purity, advanced pharmaceutical intermediate featuring a constrained diazabicyclo[4.2.0]octane scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) with potential neurological or therapeutic activity.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its rigid, three-dimensional structure.
• Process Development: Serves as a critical starting material or intermediate in scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Library Synthesis: Valuable scaffold for constructing diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying enzyme function or protein-protein interactions.
• Fine Chemical Synthesis: Intermediate for the preparation of specialized, high-value chemicals with complex stereochemistry.

Basic Information

Item	Details
Product Name	cis-8-Benzyl 3-tert-Butyl 3,8-Diazabicyclo[4.2.0]Octane-3,8-Dicarboxylate
CAS No.	1293940-93-8
Molecular Formula	C21H30N2O4
Molecular Weight	374.48 g/mol
Synonyms	8-Benzyl 3-tert-butyl 3,8-diazabicyclo[4.2.0]octane-3,8-dicarboxylate; 3,8-Diazabicyclo[4.2.0]octane-3,8-dicarboxylic acid, 8-(phenylmethyl)-, 1,1-dimethylethyl ester; 3-tert-Butyl 8-benzyl 3,8-diazabicyclo[4.2.0]octane-3,8-dicarboxylate; cis-3,8-Diazabicyclo[4.2.0]octane-3,8-dicarboxylic acid, 8-benzyl 3-tert-butyl ester; BOC-DBCO-Benzyl ester (related); DBCO derivative intermediate.
EINECS	Contact for details

Quality Control

Our cis-8-Benzyl 3-tert-Butyl 3,8-Diazabicyclo[4.2.0]Octane-3,8-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.