Description

Bocnh-Peg7-Oh CAS NO 1292268-13-3 is a specialized heterobifunctional polyethylene glycol (PEG) derivative featuring a tert-butyloxycarbonyl (Boc) protected amine group at one terminus and a hydroxyl group at the other. This compound is a critical building block in bioconjugation and pharmaceutical development, enabling the controlled synthesis of peptide and protein conjugates with enhanced solubility and pharmacokinetic properties. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, advanced drug delivery systems, and diagnostic reagent development.

Application

• Bioconjugation Linker: Used as a spacer or linker for attaching drugs, dyes, or targeting ligands to peptides, proteins, or antibodies.
• PEGylation Reagent: Serves as a key intermediate in the synthesis of PEGylated therapeutic proteins to improve stability and reduce immunogenicity.
• Solid-Phase Peptide Synthesis (SPPS): Employed for the introduction of hydrophilic PEG segments during the synthesis of complex peptides.
• Prodrug Synthesis: Facilitates the creation of cleavable prodrug constructs where the Boc group allows for selective deprotection.
• Cross-linking Agent: Acts as a heterobifunctional cross-linker for creating hydrogels or modifying biomaterial surfaces.
• Diagnostic Reagents: Used in the development of contrast agents and fluorescent probes for imaging applications.

Basic Information

Product Name	Bocnh-Peg7-Oh
CAS No.	1292268-13-3
Molecular Formula	C24H47NO10
Molecular Weight	509.64 g/mol
Synonyms	2-{2-[2-(2-{2-[2-(2-{[(tert-Butoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethanol; Boc-NH-PEG7-OH; Boc-Amino-PEG7-Alcohol; tert-Butyl N-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate; α-Boc-amino-ω-hydroxy heptaethylene glycol; Boc-8-amino-3,6-dioxaoctyl-PEG4-OH; BocNH-PEG7-OH; Boc-N-amido-PEG7-OH
EINECS	Contact for details

Quality Control

Our Bocnh-Peg7-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.