Description

8-(Morpholin-4-Ylsulfonyl)[1,2,4]Triazolo[4,3-A]Pyridin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyridine core functionalized with a morpholine sulfonyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Employed in the design and synthesis of chemical probes to investigate specific biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals due to its heterocyclic structure.

Basic Information

Product Name	8-(Morpholin-4-Ylsulfonyl)[1,2,4]Triazolo[4,3-A]Pyridin-3(2H)-One
CAS No.	1291486-75-3
Molecular Formula	C11H12N4O3S
Molecular Weight	280.30 g/mol
Synonyms	8-(Morpholin-4-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one; 8-Morpholinosulfonyl-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-3-one; 1291486-75-3; 8-(Morpholine-4-sulfonyl)-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-3-one; 8-(4-Morpholinylsulfonyl)-2H-[1,2,4]triazolo[4,3-a]pyridin-3-one; Triazolopyridine sulfonamide derivative
EINECS	Contact for details

Quality Control

Our 8-(Morpholin-4-Ylsulfonyl)[1,2,4]Triazolo[4,3-A]Pyridin-3(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.