Description

(1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-2-Yl)Methanol CAS NO 1291384-33-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl piperidine-pyridine hybrid structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of kinase inhibitors and central nervous system (CNS) targeted drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small molecule discovery.
• Kinase Inhibitor Development: The bromopyridine and sulfonamide motifs make it a valuable precursor for synthesizing compounds targeting various kinase enzymes.
• CNS Drug Discovery: The piperidine-methanol scaffold is relevant for creating molecules designed to cross the blood-brain barrier.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	(1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-2-Yl)Methanol
CAS No.	1291384-33-2
Molecular Formula	C11H15BrN2O3S
Molecular Weight	335.22 g/mol
Synonyms	2-Piperidinemethanol, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1-[(5-Bromopyridin-3-yl)sulfonyl]piperidin-2-ylmethanol; (1-((5-Bromopyridin-3-yl)sulfonyl)piperidin-2-yl)methanol; 1-(5-Bromopyridine-3-sulfonyl)piperidin-2-ylmethanol; 1-(5-Bromo-3-pyridinesulfonyl)-2-piperidinemethanol; 1291384-33-2; (1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-2-Yl)Methanol
EINECS	Contact for details

Quality Control

Our (1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.