Description

tert-Butyl4-(4-Formyl-2-Methoxyphenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and protected amine functionality. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and receptor-targeting drugs. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and scale-up production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites (aldehyde and protected amine).
• Process Chemistry Development: Serves as a critical starting material or intermediate in the development of scalable, GMP-compliant synthetic routes for APIs.
• Custom Synthesis: Employed in the contract manufacturing of specialized, high-value compounds for preclinical and clinical trials.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl4-(4-Formyl-2-Methoxyphenyl)Piperazine-1-Carboxylate
CAS No.	1290181-34-8
Molecular Formula	C17H24N2O4
Molecular Weight	320.39 g/mol
Synonyms	1-Boc-4-(4-Formyl-2-methoxyphenyl)piperazine; 4-(4-Formyl-2-methoxyphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(4-formyl-2-methoxyphenyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-formyl-2-methoxyphenyl)piperazine; BOC-4-(4-FORMYL-2-METHOXYPHENYL)PIPERAZINE; 1290181-34-8; 4-(4-Formyl-2-methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(4-Formyl-2-Methoxyphenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.