Description

1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-3-Ol is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure combining pyrazine and piperidine motifs. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and development of compounds intended for neurological and psychiatric disorders.
• Oncology Research: Employed as a building block for novel small-molecule inhibitors and targeted cancer therapies.
• Contract Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Biochemical Tool Compound: May be used in vitro to study biological pathways and mechanisms of action.

Basic Information

Product Name	1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-3-Ol
CAS No.	1289388-51-7
Molecular Formula	C11H17N3O
Molecular Weight	207.27 g/mol
Synonyms	3-Piperidinol, 1-[1-(2-pyrazinyl)ethyl]-; 1-[1-(Pyrazin-2-yl)ethyl]piperidin-3-ol; 1-(1-(Pyrazin-2-yl)ethyl)piperidin-3-ol; 1-(1-Pyrazin-2-ylethyl)piperidin-3-ol; 1-(1-Pyrazin-2-yl-ethyl)-piperidin-3-ol; Piperidin-3-ol, 1-[1-(2-pyrazinyl)ethyl]-; 1289388-51-7
EINECS	Contact for details

Quality Control

Our 1-(1-Pyrazin-2-Yl-Ethyl)-Piperidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.