Description

4-[Methyl-(3-Methyl-Pyrazin-2-Yl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Used as a core scaffold or fragment for constructing complex molecular architectures in API synthesis.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in route scouting and process development for the efficient, scalable production of target molecules.
• Contract Manufacturing: Supplied to CDMOs for the cGMP-compliant production of clinical trial materials and commercial APIs.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications.

Basic Information

Product Name	4-[Methyl-(3-Methyl-Pyrazin-2-Yl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1289388-48-2
Molecular Formula	C16H26N4O2
Molecular Weight	306.41 g/mol
Synonyms	4-[Methyl(3-methylpyrazin-2-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-[N-methyl-N-(3-methyl-2-pyrazinyl)amino]piperidine; tert-Butyl 4-[methyl(3-methylpyrazin-2-yl)amino]piperidine-1-carboxylate; 4-(Methyl(3-methylpyrazin-2-yl)amino)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[methyl(3-methyl-2-pyrazinyl)amino]piperidine; BOC-4-(N-Methyl-N-(3-methyl-2-pyrazinyl)amino)piperidine
EINECS	Contact for details

Quality Control

Our production of 4-[Methyl-(3-Methyl-Pyrazin-2-Yl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material produced under quality guidelines suitable for pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.