Description

4-(4-Chloro-Benzenesulfonylmethyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonylmethyl-piperidine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• API Development: Serves as a precursor in the development and scale-up of new active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the custom manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	4-(4-Chloro-Benzenesulfonylmethyl)-Piperidine Hydrochloride
CAS No.	1289387-34-3
Molecular Formula	C13H17Cl2NO2S
Molecular Weight	322.25 g/mol
Synonyms	4-[(4-Chlorophenyl)sulfonylmethyl]piperidine hydrochloride; 1-[(4-Chlorophenyl)sulfonylmethyl]-4-piperidine hydrochloride; 4-(4-Chlorobenzenesulfonylmethyl)piperidine HCl; Piperidine, 4-[(4-chlorophenyl)sulfonylmethyl]-, hydrochloride; 1289387-34-3
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Benzenesulfonylmethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.