Description

Methyl-[1-(2-Methyl-Benzyl)-Piperidin-3-Yl]-Amine Hydrochloride CAS NO 1289387-26-3 is a high-purity, pharmaceutically relevant piperidine derivative supplied as a hydrochloride salt. This compound is a critical building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probe Development: Used in the design and synthesis of molecular probes for studying enzyme function and receptor-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl-[1-(2-Methyl-Benzyl)-Piperidin-3-Yl]-Amine Hydrochloride
CAS No.	1289387-26-3
Molecular Formula	C15H24N2·HCl
Molecular Weight	268.83 g/mol (free base: 232.36 g/mol)
Synonyms	N-Methyl-1-(2-methylbenzyl)piperidin-3-amine hydrochloride; 1-(2-Methylbenzyl)-N-methylpiperidin-3-amine HCl; 3-[(Methylamino)methyl]-1-(2-methylbenzyl)piperidine hydrochloride; Methyl-(1-(2-methylbenzyl)-3-piperidyl)amine hydrochloride; (R/S)-Methyl-[1-(2-methyl-benzyl)-piperidin-3-yl]-amine hydrochloride; 1289387-26-3
EINECS	Contact for details

Quality Control

Our Methyl-[1-(2-Methyl-Benzyl)-Piperidin-3-Yl]-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR, MS). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.