Description

3-(2-Chloro-6-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and agrochemical innovators requiring a reliable, high-quality building block for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, especially for neurological targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in multi-step synthetic routes for candidate drug molecules.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides due to its halogenated benzyl and piperidine motifs.
• Chemical Biology & Proteomics: Employed as a scaffold or ligand in the design of molecular probes for studying biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	3-(2-Chloro-6-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride
CAS No.	1289386-70-4
Molecular Formula	C14H19ClFNO•HCl
Molecular Weight	308.22 g/mol (for free base: 271.76 g/mol)
Synonyms	3-[(2-Chloro-6-fluorophenyl)methoxy]methyl]piperidine hydrochloride; 1-(2-Chloro-6-fluorobenzyloxymethyl)piperidine-3-hydrochloride; 2-Chloro-6-fluoro-((3-piperidinylmethoxy)methyl)benzene hydrochloride; Piperidine, 3-[[(2-chloro-6-fluorophenyl)methoxy]methyl]-, hydrochloride (1:1); CAS 1289386-70-4
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chloro-6-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot, supporting development under cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.