Description

1-(6-Bromo-Pyridin-2-Yl)-Azetidine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a critical scaffold for constructing complex molecules, particularly in the development of new active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical researchers, agrochemical formulators, and specialty chemical manufacturers need this intermediate for its unique azetidine and bromopyridine moieties, which are essential for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in CDMO (Contract Development and Manufacturing Organization) facilities.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and organic synthesis laboratories for exploring new chemical space.

Basic Information

Product Name	1-(6-Bromo-Pyridin-2-Yl)-Azetidine-3-Carboxylic Acid
CAS No.	1289386-69-1
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	1-(6-Bromopyridin-2-yl)azetidine-3-carboxylic acid; Azetidine-3-carboxylic acid, 1-(6-bromo-2-pyridinyl)-; 3-Carboxy-1-(6-bromo-2-pyridyl)azetidine; 1-(6-Bromo-2-pyridyl)azetidine-3-carboxylic acid; 1289386-69-1; 1-(6-Bromopyridin-2-yl)azetidine-3-carboxylic acid (Azetidine derivative)
EINECS	Contact for details

Quality Control

Our 1-(6-Bromo-Pyridin-2-Yl)-Azetidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply for global research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.