Description

Methyl-[1-(3-Methyl-Pyrazin-2-Yl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound, with CAS number 1289386-22-6, is a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially within central nervous system (CNS) research.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block for constructing complex molecular architectures in final API manufacturing.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Process Chemistry & Scale-Up: Employed in route scouting, process development, and the scale-up of synthetic pathways from milligram to kilogram scale.
• Reference Standard: Can be utilized as an analytical reference standard for quality control and method development in pharmaceutical analysis.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary compounds for specialized research programs.

Basic Information

Item	Detail
Product Name	Methyl-[1-(3-Methyl-Pyrazin-2-Yl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1289386-22-6
Molecular Formula	C16H26N4O2
Molecular Weight	306.41 g/mol
Synonyms	tert-Butyl methyl[1-(3-methylpyrazin-2-yl)piperidin-3-yl]carbamate; N-Boc-N-methyl-1-(3-methylpyrazin-2-yl)piperidin-3-amine; 1-(3-Methylpyrazin-2-yl)-3-[(tert-butoxycarbonyl)(methyl)amino]piperidine; BOC-Protected Methylamino Piperidine Pyrazine Derivative; CAS 1289386-22-6; Methyl-(1-(3-methyl-pyrazin-2-yl)-piperidin-3-yl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Methyl-[1-(3-Methyl-Pyrazin-2-Yl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We support development under cGMP guidelines where required, ensuring reliability for critical research and pre-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.