Description

4-(1-Pyrazin-2-Yl-Ethoxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound is critical for medicinal chemistry research and development, particularly in the construction of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex target molecules for clinical development.
• Chemical Biology: Employed in the development of chemical probes and tools for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Process Chemistry: Used in route scouting and scale-up development for new chemical entities (NCEs).

Basic Information

Product Name	4-(1-Pyrazin-2-Yl-Ethoxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1289385-77-8
Molecular Formula	C17H25N3O3
Molecular Weight	319.40 g/mol
Synonyms	tert-Butyl 4-[(1-pyrazin-2-ylethoxy)methyl]piperidine-1-carboxylate; 1-Boc-4-[(1-pyrazin-2-ylethoxy)methyl]piperidine; 1-(tert-Butoxycarbonyl)-4-[(1-pyrazin-2-ylethoxy)methyl]piperidine; 4-[(1-Pyrazin-2-ylethoxy)methyl]piperidine-1-carboxylic acid tert-butyl ester; BOC-Piperidine-Pyrazine Derivative; 1289385-77-8; 4-(1-Pyrazin-2-Yl-Ethoxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 4-(1-Pyrazin-2-Yl-Ethoxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.