Description

3-(2,6-Dichloro-Benzyloxy)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API synthesis under GMP conditions.
• Reference Standard: Employed as an analytical standard for method development and quality control in API manufacturing.
• Biochemical Research: Used as a tool compound for investigating biological pathways and receptor interactions.
• Custom Synthesis: Basis for the preparation of more complex, proprietary molecules for client-specific projects.

Basic Information

Product Name	3-(2,6-Dichloro-Benzyloxy)-Piperidine Hydrochloride
CAS No.	1289385-64-3
Molecular Formula	C12H15Cl2NO • HCl
Molecular Weight	296.62 g/mol (Free base: 260.16 g/mol)
Synonyms	3-[(2,6-Dichlorophenyl)methoxy]piperidine hydrochloride; 3-(2,6-Dichlorobenzyloxy)piperidine HCl; Piperidine, 3-[(2,6-dichlorophenyl)methoxy]-, hydrochloride (1:1); 1289385-64-3; UNII-9Q8F7Q9F5M; 9Q8F7Q9F5M; 3-(2,6-Dichloro-benzyloxy)-piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(2,6-Dichloro-Benzyloxy)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.