Description

4-(Pyrazin-2-Ylamino)-Cyclohexanol CAS NO 1289385-10-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazine-cyclohexanol hybrid structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic molecules and exploring structure-activity relationships (SAR).
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for pharmacological and chemical research.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential new chemical entities (NCEs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	4-(Pyrazin-2-Ylamino)-Cyclohexanol
CAS No.	1289385-10-9
Molecular Formula	C10H15N3O
Molecular Weight	193.25 g/mol
Synonyms	4-[(Pyrazin-2-yl)amino]cyclohexanol; 4-(Pyrazin-2-ylamino)cyclohexan-1-ol; Cyclohexanol, 4-[(2-pyrazinyl)amino]-; 1289385-10-9; 4-(2-Pyrazinylamino)cyclohexanol; 4-(Pyrazin-2-ylamino)-1-cyclohexanol
EINECS	Contact for details

Quality Control

Our 4-(Pyrazin-2-Ylamino)-Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.