Description

1-(2-Methyl-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, enabling the construction of complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Peptidomimetics & Drug Discovery: Serves as a constrained scaffold in medicinal chemistry for designing peptide analogs and small molecule libraries.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Catalyst & Ligand Preparation: Potential precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-(2-Methyl-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride
CAS No.	1289384-92-4
Molecular Formula	C14H20N2O2·HCl
Molecular Weight	284.78 g/mol
Synonyms	1-[(2-Methylphenyl)methyl]piperazine-2-carboxylic acid hydrochloride; (2S)-1-[(2-Methylphenyl)methyl]piperazine-2-carboxylic acid hydrochloride; 2-Piperazinecarboxylic acid, 1-[(2-methylphenyl)methyl]-, hydrochloride (1:1); 1-(2-Methylbenzyl)piperazine-2-carboxylic acid HCl; (S)-1-(2-Methylbenzyl)piperazine-2-carboxylic acid hydrochloride; 2-Methylbenzyl-piperazine-2-carboxylic acid hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-(2-Methyl-Benzyl)-Piperazine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.