Description

5-Bromo-3-Methyl-2-(Methylthio)Pyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research, enabling the development of new active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and sulfur substituents for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis or for creating specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form more complex biaryl structures.

Basic Information

Product Name	5-Bromo-3-Methyl-2-(Methylthio)Pyridine
CAS No.	1289270-74-1
Molecular Formula	C8H8BrNS
Molecular Weight	232.12 g/mol
Synonyms	2-(Methylthio)-5-bromo-3-methylpyridine; 3-Methyl-2-(methylthio)-5-bromopyridine; 5-Bromo-3-methyl-2-methylsulfanylpyridine; 5-Bromo-2-methylsulfanyl-3-methylpyridine; 2-Methylsulfanyl-5-bromo-3-methylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-2-(Methylthio)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.