Description

3-Chloro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique combination of a pyrrolopyridine scaffold with chloro and trifluoromethyl substituents, enabling precise molecular modifications and the introduction of desirable physicochemical properties. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in drug discovery programs targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the biological activity of the pyrrolopyridine core.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional dyes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1289197-40-5
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-(trifluoromethyl)-7-azaindole; 3-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-(trifluoromethyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, keep at 2-8°C under an inert atmosphere. The compound is moisture-sensitive; ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.