Description

2-Bromo-5-Methoxypyridine-3-Carbaldehyde is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a bromine substituent on the methoxypyridine scaffold, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular components for conductive polymers.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi), enabling rapid diversification of the pyridine core.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological processes and protein interactions.

Basic Information

Item	Details
Product Name	2-Bromo-5-Methoxypyridine-3-Carbaldehyde
CAS No.	1289177-58-7
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	5-Methoxy-2-bromopyridine-3-carboxaldehyde; 3-Formyl-2-bromo-5-methoxypyridine; 2-Bromo-5-methoxy-3-pyridinecarboxaldehyde; 2-Bromo-5-methoxynicotinaldehyde; (2-Bromo-5-methoxypyridin-3-yl)methanal; 1289177-58-7; Aldehyde, 2-bromo-5-methoxy-3-pyridinecarbox-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Methoxypyridine-3-Carbaldehyde is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.