Description

4-Amino-5-Chloronicotinaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive aldehyde and amino groups.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research labs.
• Material Science: Potential precursor for the synthesis of functionalized ligands, dyes, or coordination polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	4-Amino-5-Chloronicotinaldehyde
CAS No.	1289175-56-9
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	5-Chloro-4-aminonicotinaldehyde; 5-Chloro-4-pyridinamine-3-carboxaldehyde; 3-Formyl-5-chloro-4-aminopyridine; 4-Amino-5-chloro-3-pyridinecarboxaldehyde; 4-Amino-5-chloropyridine-3-carbaldehyde; 5-Chloro-4-amino-3-formylpyridine; 4-Amino-5-chloro-3-formylpyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloronicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.