Description

6-Chloro-5-Iodonicotinaldehyde is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional aldehyde and halogenated structure makes it an indispensable precursor for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling reactions and other metal-mediated processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create labeled probes and molecular tags for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Chloro-5-Iodonicotinaldehyde
CAS No.	1288991-51-4
Molecular Formula	C6H3ClINO
Molecular Weight	283.45 g/mol
Synonyms	5-Iodo-6-chloropyridine-3-carbaldehyde; 3-Formyl-5-iodo-6-chloropyridine; 6-Chloro-5-iodo-3-pyridinecarboxaldehyde; 6-Chloro-5-iodonicotinaldehyde; 5-Iodo-6-chloronicotinaldehyde; Nicotinaldehyde, 6-chloro-5-iodo-; (6-Chloro-5-iodopyridin-3-yl)methanol (oxidized form)
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.