Description

5-Cyclobutoxypyridine-2-Carboxylic Acid is a high-value pyridine derivative carboxylic acid, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclobutyl ether linkage, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	5-Cyclobutoxypyridine-2-Carboxylic Acid
CAS No.	1286777-31-8
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-(cyclobutyloxy)-; 5-(Cyclobutoxy)picolinic acid; 5-Cyclobutoxy-2-pyridinecarboxylic acid; 2-Carboxy-5-cyclobutoxypyridine; Cyclobutyl 5-carboxypyridin-2-yl ether; Picolinic acid, 5-cyclobutoxy-; CAS 1286777-31-8
EINECS	Contact for details

Quality Control

Our 5-Cyclobutoxypyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.