Description

(R)-2-n-Cbz-Aminomethylmorpholine CAS NO 1286768-73-7 is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical purity is paramount. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in asymmetric synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex, enantiomerically pure molecules in medicinal chemistry.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetic compounds due to its morpholine and protected amine functionality.
• Ligand and Catalyst Development: Employed as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Academic and R&D Laboratories: Essential for chemical research focusing on new synthetic methodologies and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(R)-2-n-Cbz-Aminomethylmorpholine
CAS No.	1286768-73-7
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	(R)-4-((((Benzyloxy)carbonyl)amino)methyl)morpholine-2-carboxylic acid; (R)-2-Carboxy-4-((N-Cbz-amino)methyl)morpholine; (R)-N-Cbz-Aminomethylmorpholine-2-carboxylic Acid; (R)-2-(Cbz-Aminomethyl)morpholine-4-carboxylic Acid; (2R)-4-({[(Benzyloxy)carbonyl]amino}methyl)morpholine-2-carboxylic Acid; (R)-Cbz-Ammor; (R)-2-Carboxy-N-Cbz-morpholine
EINECS	Contact for details

Quality Control

Our (R)-2-n-Cbz-Aminomethylmorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.