Description

6-Cbz-3,6-Diaza-Bicyclo[3.2.0]Heptane CAS NO 1286754-54-8 is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic diaza structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug molecules, especially those targeting the central nervous system and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical entities in drug discovery and lead optimization programs.
• Process Chemistry & Scale-up: Employed in the development and optimization of robust, scalable synthetic routes for API manufacturing.
• Proteolysis Targeting Chimera (PROTAC) Development: Its structural features make it a potential component in the linker or warhead design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity, nitrogen-rich bicyclic frameworks.

Basic Information

Product Name	6-Cbz-3,6-Diaza-Bicyclo[3.2.0]Heptane
CAS No.	1286754-54-8
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	6-[(Benzyloxy)carbonyl]-3,6-diazabicyclo[3.2.0]heptane; 3,6-Diaza-bicyclo[3.2.0]heptane-6-carboxylic acid benzyl ester; 6-Cbz-3,6-diazabicyclo[3.2.0]heptane; 6-(Benzyloxycarbonyl)-3,6-diazabicyclo[3.2.0]heptane; Benzyl 3,6-diazabicyclo[3.2.0]heptane-6-carboxylate; 6-Cbz-3,6-DABH; CAS 1286754-54-8
EINECS	Contact for details

Quality Control

Our 6-Cbz-3,6-Diaza-Bicyclo[3.2.0]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.