Description

1H-Pyrazolo[3,4-B]Pyrazine-3-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate in modern organic chemistry. Its fused pyrazolo-pyrazine core structure makes it a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Development: Used in the research and synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: Essential for methodological development in organic synthesis and medicinal chemistry within university and CRO laboratories.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyrazine-3-Carboxylic Acid
CAS No.	1286754-47-9
Molecular Formula	C6H4N4O2
Molecular Weight	164.12 g/mol
Synonyms	Pyrazolo[3,4-b]pyrazine-3-carboxylic acid; 1H-Pyrazolo[3,4-b]pyrazine-3-carboxylic acid; 3-Pyrazolo[3,4-b]pyrazinecarboxylic acid; 1H-Pyrazolo[3,4-b]pyrazine-3-carboxylic acid (9CI); 1286754-47-9 (CAS); Pyrazolopyrazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyrazine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with strong acids and organic solvents but should be kept separate from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.