Description

tert-Butyl 4-(4-Cyanobenzoylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a 4-cyanobenzamide moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the development of inhibitors for various protease enzymes, leveraging the piperidine scaffold.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of small molecule kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 4-(4-Cyanobenzoylamino)Piperidine-1-Carboxylate
CAS No.	1286275-34-0
Molecular Formula	C18H23N3O3
Molecular Weight	329.40 g/mol
Synonyms	1-Boc-4-[(4-cyanobenzoyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-4-[(4-cyanobenzoyl)amino]piperidine; 4-[(4-Cyanobenzoyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[(4-cyanobenzoyl)amino]piperidine-1-carboxylate; 4-(4-Cyanobenzamido)piperidine-1-carboxylic acid tert-butyl ester; N-(1-Boc-4-piperidyl)-4-cyanobenzamide; BOC-4-(4-Cyanobenzamido)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Cyanobenzoylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if frequent access is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.