Description

tert-Butyl 1-(4-Hydroxybenzyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine carbamate scaffold with a phenolic functional group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a precursor for creating more complex molecules with piperidine and carbamate functionalities.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Bioconjugation & Probe Development: The reactive hydroxybenzyl group can be utilized for conjugation chemistry in developing biochemical probes.

Basic Information

Product Name	tert-Butyl 1-(4-Hydroxybenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286275-25-9
Molecular Formula	C18H28N2O3
Molecular Weight	320.43 g/mol
Synonyms	1-(4-Hydroxybenzyl)-4-[(tert-butoxycarbonyl)amino]piperidine; tert-Butyl N-[1-[(4-hydroxyphenyl)methyl]piperidin-4-yl]carbamate; 4-[(tert-Butoxycarbonyl)amino]-1-(4-hydroxybenzyl)piperidine; BOC-4-Amino-1-(4-hydroxybenzyl)piperidine; 1-(4-Hydroxybenzyl)piperidin-4-amine, N-BOC-protected; tert-Butyl (1-(4-hydroxybenzyl)piperidin-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(4-Hydroxybenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.