Description

tert-Butyl 1-(5-Fluoro-2-Methoxybenzyl)Piperidin-4-Ylcarbamate CAS NO 1286274-91-6 is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carbamate core and substituted benzyl group. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• API Development: Serves as a building block in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: May be utilized in the development of probes for studying biological targets and pathways in preclinical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	tert-Butyl 1-(5-Fluoro-2-Methoxybenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286274-91-6
Molecular Formula	C19H29FN2O3
Molecular Weight	352.45 g/mol
Synonyms	tert-Butyl N-[1-[(5-Fluoro-2-methoxyphenyl)methyl]piperidin-4-yl]carbamate; 1-(5-Fluoro-2-Methoxybenzyl)Piperidin-4-Amine, N-BOC Protected; BOC-4-Amino-1-(5-Fluoro-2-Methoxybenzyl)Piperidine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[(5-fluoro-2-methoxyphenyl)methyl]piperidine; 1286274-91-6; tert-Butyl (1-((5-fluoro-2-methoxybenzyl)piperidin-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(5-Fluoro-2-Methoxybenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.