Description

tert-Butyl 1-(4-Bromobenzoyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carbamate core and bromobenzoyl functional group. This compound is of significant commercial importance for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents, including potential central nervous system (CNS) and oncology drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile piperidine scaffold.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors, leveraging its carbamate and amide functionalities.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and receptor binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	tert-Butyl 1-(4-Bromobenzoyl)Piperidin-4-Ylcarbamate
CAS No.	1286274-89-2
Molecular Formula	C17H23BrN2O3
Molecular Weight	383.28 g/mol
Synonyms	1-BOC-4-Amino-piperidine-1-(4-bromobenzoyl); tert-Butyl N-[1-[(4-bromophenyl)carbonyl]piperidin-4-yl]carbamate; 1-(4-Bromobenzoyl)-4-[(tert-butoxycarbonyl)amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(4-bromobenzoyl)piperidine; Boc-4-Amino-1-(4-bromobenzoyl)piperidine; N-Boc-4-Amino-1-(4-bromobenzoyl)piperidine; 1-(4-Bromo-benzoyl)-piperidine-4-carboxylic acid tert-butylamide (obsolete)
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(4-Bromobenzoyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.