Description

tert-Butyl 1-(2,4,6-Trifluorobenzyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluorobenzyl-piperidine carbamate structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential protease inhibitors due to its piperidine carbamate moiety.
• Ligand Synthesis: Employed in the creation of specialized ligands for biological target modulation and diagnostic agent development.
• Chemical Biology: Utilized as a tool compound for probing biological pathways and enzyme functions in research settings.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 1-(2,4,6-Trifluorobenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286274-82-5
Molecular Formula	C17H23F3N2O2
Molecular Weight	344.37 g/mol
Synonyms	1-(2,4,6-Trifluorobenzyl)piperidin-4-amine, N-Boc derivative; tert-Butyl N-[1-[(2,4,6-trifluorophenyl)methyl]piperidin-4-yl]carbamate; 4-[[(tert-Butoxy)carbonyl]amino]-1-[(2,4,6-trifluorophenyl)methyl]piperidine; 1-(2,4,6-Trifluorobenzyl)-4-[(tert-butoxycarbonyl)amino]piperidine; N-Boc-1-(2,4,6-trifluorobenzyl)piperidin-4-amine; 1286274-82-5; tert-Butyl (1-(2,4,6-trifluorobenzyl)piperidin-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(2,4,6-Trifluorobenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of pharmaceutical R&D. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.