Description

1-(2,3-Difluorobenzyl)Piperidin-4-Aminedihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its dihydrochloride salt form. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Preclinical Development: Serves as a key starting material (KSM) or advanced intermediate for producing active pharmaceutical ingredients (APIs) in gram to kilogram scales.
• Chemical Biology: Employed in the design and synthesis of chemical probes for studying biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-(2,3-Difluorobenzyl)Piperidin-4-Aminedihydrochloride
CAS No.	1286274-04-1
Molecular Formula	C12H17Cl2F2N2
Molecular Weight	298.18 g/mol
Synonyms	1-[(2,3-Difluorophenyl)methyl]-4-piperidinamine dihydrochloride; 4-Amino-1-(2,3-difluorobenzyl)piperidine dihydrochloride; 1-(2,3-Difluorobenzyl)-4-aminopiperidine dihydrochloride; 4-Piperidinamine, 1-[(2,3-difluorophenyl)methyl]-, dihydrochloride; 1-(2,3-Difluorobenzyl)piperidin-4-amine 2HCl; 1286274-04-1; 1-(2,3-Difluorobenzyl)-4-piperidinamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorobenzyl)Piperidin-4-Aminedihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.